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The width of the QRS is often used to
2019-06-29

The width of the QRS is often used to ascertain the distance of the site of origin from the conduction system. In the absence of antiarrhythmics, which result in conduction slowing, VTs with narrow QRS are located closer to the purkinje system or septum. VTs originating from the epicardium have been
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La conclusi n principal que podemos
2019-06-29

La conclusión principal que podemos extraer de la lectura de los discursos de los sujetos que conforman organizaciones sociales urbanas contemporáneas de Argentina y Uruguay, es que la integración regional se sostiene como una aspiración. Se trata de un proyecto que es considerado factible, pero que
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En este proceso de integraci
2019-06-29

En este proceso de integración y unidad latinoamericana y caribeña, la imagen política y diplomática de Estados Unidos se vio seriamente mermada por su terrible campaña contra el terrorismo. Su economía se mantiene sumergida en una aguda crisis financiera desde 2008, la más profunda desde 1929. A pe
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Delays in diagnosis due to the
2019-06-29

Delays in diagnosis due to the subtlety and focal nature of the intravascular infiltrates often lead to a terminal disease with death before chemotherapy is initiated. R-CHOP plus CNS prophylaxis is the treatment of choice in patients [30,31] without Sobetirome structure involvement. CNS involvemen
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Since the progressive introduction of the meningococcal
2019-06-29

Since the progressive introduction of the meningococcal serogroup A conjugate vaccine in meningitis belt countries via mass vaccination campaigns of 1–29 year olds starting in 2010, a remarkable effect of the vaccine has been observed. Similar to other conjugate vaccines, MenAfriVac has demonstrated
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br Other candidate genes br The frequency
2019-06-29

Other candidate genes The frequency of minor gene mutations in BrS As mentioned above, more than 10 genes have been reported to cause BrS. The proportions of BrS patients who are mutation carriers, however, are very small, except in the case of SCN5A. In a recent extensive mutation analysis of
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Un peculiar texto de Borges enumera al interior
2019-06-28

Un peculiar texto de Borges enumera, al interior de su relato, interesantes ejemplos de varias categorías pertenecientes al idioma propuesto por John Wil-kins —un sabio inglés del siglo — cuyo objetivo fue diseñar un lenguaje mucho más completo, abarcador e incluso preciso, en sus descripciones del
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In this issue of Jun Zhu and colleagues
2019-06-28

In this issue of , Jun Zhu and colleagues report data retrieved from China\'s National Maternal Near Miss Surveillance System (NMNMSS), yielding a stillbirth rate of 8·8 per 1000 births for the Rucaparib free base weight 2012–14. By comprehensively incorporating datasets based on level II (county o
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In contrast to the low
2019-06-28

In COG 133 weight to the low insertion frequency in Asian population for HERV-K113 (13%) and -K115 (4%) [10], we demonstrate herein high insertion frequency (89.3%) of HERV-H in the Singapore population, and observe interesting correlation between prevalence and age-standardized incidence rate of H
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br Conclusion br Introduction Multiple myeloma
2019-06-28

Conclusion Introduction Multiple myeloma is a malignant plasma cell disorder, comprising approximately 10% of all haematological malignancies, and its incidence is increasing [1]. The pathogenesis is complex, culminating in malignant transformation of clonal plasma cells. The aetiology is not
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Although the CHADS score is useful for evaluating the risk
2019-06-28

Although the CHADS2 score is useful for evaluating the risk of stroke in NVAF patients, about half of all NVAF patients have a score of 0 or 1 [7]. There are no clear guidelines on whether warfarin should be administered or not, to these patients because the risk of annual incidence of stroke is so
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In this case report we
2019-06-28

In this case report, we described a rare case of tumor lysis syndrome associated with the FOLFOX regimen and further stress the importance of additional prophylaxis for the huge tumor burden. Our patient\'s hyperammonemia may be due to cardiogenic shock, post cardio-pulmonary-cerebral resuscitation
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The main inherited arrhythmogenic causes of
2019-06-28

The main inherited arrhythmogenic causes of SCD in the young are summarized in Fig. 1. These arrhythmogenic disorders include familial long QT syndrome (LQTS), catecholaminergic polymorphic ventricular tachycardia (CPVT), Brugada syndrome (BrS), idiopathic ventricular fibrillation, early repolarizat
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In silico prediction software SIFT PolyPhen CADD and other
2019-06-28

In silico prediction software, SIFT [51], PolyPhen2 [52], CADD [53], and other prediction systems are useful to evaluate a specific mutation which is detected in a patient. However, even if the in silico software predicts a mutation as pathogenic, we need to examine whether the genetic result is com
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Two other groups subsequently published further
2019-06-27

Two other groups subsequently published further data on iPSCs models of ARVC that have improved our understanding of this disease. Kim et al. developed iPSC models using episomal methods from 2 ARVC patients, as well as with PKP2 mutations . Detailed electrophysiological characterization of mutant a
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